and transmitted securely. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking isosorbide. Consult your pharmacist or local waste disposal company. A very serious allergic reaction to this drug is rare. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. (1) Starting on a low dosage was associated with a reduced frequency and severity of headache and did not notably influence the beneficial effect on angina pectoris. Some conditions may become worse when the drug is suddenly stopped. There are no data on passage of isosorbide mononitrate in human milk, but some excretion seems likely. Available for Android and iOS devices. To use the sharing features on this page, please enable JavaScript. Data were assessed for carryover and time effects. Patient does not provide medical advice, diagnosis or treatment. Liperoti R, et al. Always consult your healthcare provider. Some products that may interact with this drug include: drugs to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), riociguat. The American Society of Health-System Pharmacists, 4500 East-West Highway, Suite 900, Bethesda, Maryland. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or . Things to remember when you fill your prescription. 2006 Apr;95(4):217-23. doi: 10.1007/s00392-006-0367-x. Coenzyme Q-10 Natural Medicines. 2017; doi:10.1016/j.jacc.2016.11.078. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Ask your pharmacist for a list of the ingredients. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks ( chest pain ). Taking erectile dysfunction medications or drinking alcohol while taking isosorbide mononitrate (Monoket) can cause your blood pressure to get dangerously low, which can be life-threatening. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. It might help to take isosorbide mononitrate and dinitrate after meals. Some don't work well with prescription medicines. 7 disease interactions. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. However, you should not flush this medication down the toilet. Many people using this medication do not have serious side effects. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. MBBS, MS - General Surgery, mch neuro surgery. All rights reserved. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Do not share this medication with others. Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. Hawthorn. Read our editorial policy. Commonly reported side effects include: See also: isosorbide mononitrate side effects in more detail. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to similar drugs (such as isosorbide dinitrate, nitroglycerin); or if you have any other allergies. Isosorbide immediate-release tablets are used for the management of angina (chest pain) in people who have coronary artery disease (narrowing of the blood vessels that supply blood to the heart). What conditions does Isosorbide Mononitrate treat? Some of these interactions can be life-threatening. Generic alternatives may be available. Mayo Clinic does not endorse companies or products. Saw palmetto. Does isosorbide mononitrate (Monoket) lower blood pressure? Cao HY, Wu HD, Song ZK, Tang ML, Yang S, Liu Y, Qin L. Pan Afr Med J. Using this medicine with any of the following medicines is not recommended. Headache, dizziness, lightheadedness, nausea, and flushing may occur as your body adjusts to this medication. 67% of reviewers reported a positive effect, while 13% reported a negative effect. If you notice other effects not listed above, contact your doctor or pharmacist. Ask your doctor before using aspirin together with alcohol. It is particularly important that you tell your doctor if you are using any medicines to help treat erectile dysfunction. 1998 Oct;61(10):577-83. This medication belongs to a class of drugs known as nitrates. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. ask your doctor about the safe use of alcoholic beverages while you are taking isosorbide. Isosorbide mononitrate is also sometimes prescribed alongside other medicines for people with heart failure. Copyright, 2023. It will not treat an angina attack that has already begun. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. Consult your doctor before breast-feeding. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. Diabetes treatment: Can cinnamon lower blood sugar? If you experience any other symptoms which you think may be due to the medicine, please speak with your doctor or pharmacist for further advice. There may be variations in CSA schedules between individual states. The narrowing makes it more difficult for blood to flow to your heart muscle. Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. It will not treat an angina attack that has already begun. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Murray MT. Talk to your doctor if you are using marijuana (cannabis). It also relaxes and widens blood vessels in your heart (coronary arteries) which increases the flow of blood to your heart muscle. Even if the medication is working, you may experience some unwanted side effects. Be sure to mention any of the following: aspirin; beta blockers such as atenolol (Tenormin, Tenoretic), carteolol , labetalol (Trandate), metoprolol (Lopressor, Toprol-XL, in Dutoprol, in Lopressor HCT), nadolol (Corgard, in Corzide), propranolol (Hemangeol, Inderal, Innopran), sotalol (Betapace, Sorine, Sotylize), and timolol; calcium channel blockers such as amlodipine (Norvasc, in Amturnide, in Tekamlo), diltiazem (Cardizem, Cartia, Dilt-CD, others), felodipine (Plendil), isradipine, nifedipine (Adalat CC, Afeditab, Procardia), and verapamil (Calan, Covera, Verelan); ergot-type medications such as bromocriptine (Cycloset, Parlodel), cabergoline, dihydroergotamine (D.H.E. 5.0 out of 10 from a total of Headaches can be a sign that the medicine is working, and they might lessen with continued use of the medication. Isosorbide mononitrate belongs to the group of medicines called nitrates. Consult your doctor for more details. Before Normal ecg doesn't rule out heart disease. A single copy of these materials may be reprinted for noncommercial personal use only. If we combine this information with your protected coma (loss of consciousness for a period of time). Isosorbide mononitrate (Monoket) is a nitrate vasodilator. Licorice. All rights reserved. Properly discard this product when it is expired or no longer needed. Keep all medicines out of the reach and sight of children. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Isosorbide may cause other side effects. This site needs JavaScript to work properly. There are a number of medications that your doctor can prescribe in place of isosorbide mononitrate (Monoket). Along with its needed effects, a medicine may cause some unwanted effects. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. Patient aims to help the world proactively manage its healthcare, supplying evidence-based information on a wide range of medical and health topics to patients and health professionals. Some of the common derivatives include isosorbide dinitrate and isosorbide mononitrate, which are . B complex. Isosorbide mononitrate 30% immediate-release 70% sustained-release formulation: a review. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.AvanafilRiociguatSildenafilTadalafilVardenafil. Never take more than the prescribed dose. Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. You can take your doses either before or after meals. Anti-ischemic and anti-anginal effects of controlled-release and conventional isosorbide-5-mononitrate in stable angina pectoris. Usually avoid combinations; use it only under special circumstances. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. All rights reserved. You can consult me online for homeopathic treatment. Our clinical information meets the standards set by the NHS in their Standard for Creating Health Content guidance. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Isosorbide mononitrate is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). Journals of the American College of Cardiology. If you have any problems with the way your liver works, or any problems with the way your kidneys work. This medicine is a white, round, scored, tablet imprinted with "KU 107" and "20". 8.0 out of 10 from a total of You can develop a tolerance to isosorbide mononitrate (Monoket) over time, which means the dose you've been taking doesn't work as well. By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx. Let your provider know if they are excessive. Tell your doctor right away if you have any serious side effects, including: fainting, fast/irregular/pounding heartbeat. We asked 34 people what they think about isosorbide mononitrate (Monoket): Get Isosorbide mononitrate (Monoket) for as low as $29.86, 180 tablets of isosorbide mononitrate 10mg. Ginkgo. You may report side effects to the FDA at 1-800-FDA-1088. 41% of reviewers reported a positive effect, while 50% reported a negative effect. Tell your doctor if this medication stops working well (for example, you have more frequent or worsening chest pain). The longer you take isosorbide mononitrate, the more your body can become used to it (called tolerance), and then it can have less of an effect. Do not drink alcohol while taking View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. If you have recently had a head injury or a heart attack. If you miss a dose, take it as soon as you remember. Some of these medicine interactions can be risky. Accessed Sept. 7, 2022. It is best not to drink alcohol while you are on isosorbide mononitrate. Bethesda, MD 20894, Web Policies 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Generic alternatives may be available. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Lyrica and Metoclopramide drug interaction, Calcitriol and Metoclopramide drug interaction. Natural Medicines. Yet significantly fewer patients had headache on low dosage than on high dosage (45 vs 57, P < 0.02). Instead, the best way to dispose of your medication is through a medicine take-back program. All rights reserved. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911. Headache is often a sign that this medication is working. Symptoms of overdose may include: slow heartbeat, vision changes, severe nausea/vomiting, sweating, cold/clammy skin, bluish fingers/toes/lips. This does not necessarily mean no interactions exist. Your provider might temporarily have you stop isosorbide mononitrate (Monoket) if this happens. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. Isosorbide mononitrate is used to prevent chest pain ( angina) in patients with a certain heart condition ( coronary artery disease ). Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction. Modified-release nitrate preparations: use a once-daily dose to maintain a nitrate-low period and thus minimize tolerance. Would you like email updates of new search results? Talk to your pharmacist for more details. . All rights reserved. information and will only use or disclose that information as set forth in our notice of https://naturalmedicines.therapeuticresearch.com. from the best health experts in the business. [2] It is taken by mouth. . 2021 May 11;39:28. doi: 10.11604/pamj.2021.39.28.22180. Accessed Sept. 7, 2022. It has a very short duration of action and may not be suitable for some people. Does Viagra add to the risks of melanoma? No you may not. I strongly feel that there is coronary ischemia. Some brands of isosorbide mononitrate tablets should be taken two or three times a day. Changing positions slowly can help lessen dizziness. it is a safe and effective alternative; the choice between beta blockers and calcium channel blockers depends . You need to take it every day in order for it to work. For haemoglobin formation vit. Isosorbide controls chest pain but does not cure coronary artery disease. The tablet usually is taken two or three times daily. It will give you more information about nitrate medicines, and it will also provide you with a full list of side-effects which you could experience from taking isosorbide mononitrate. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. http://www.upandaway.org. Meinertz T, Lehmacher W; Trapidil/ISDN Study Group. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: continuing ringing or buzzing or other unexplained noise in the ears, dull ache or feeling of pressure or heaviness in the legs, excess air or gas in the stomach or intestines, increased sensitivity of the eyes to sunlight, loss in sexual ability, desire, drive, or performance, pain or tenderness around the eyes and cheekbones, redness of the face, neck, arms, and occasionally, upper chest, redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid, redness, swelling, or soreness of the tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, stomach bloating, burning, cramping, or pain, terrifying dreams causing sleep disturbances, uncontrolled twisting movements of the neck, white patches in the mouth, tongue, or throat. Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: It's not suggested to take St. John's wort if you take blood thinners. Isosorbide mononitrate (Monoket) is not a medication you take if you think you are having a heart attack. As precautionary measure, it is preferable to avoid the use of isosorbide mononitrate during pregnancy. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. View all Check with your doctor immediately if any of the following side effects occur: burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, fast, slow, irregular, pounding, or racing heartbeat or pulse, itching, pain, redness, or swelling on the leg, numbness or tingling in the hands, feet, or lips, pain or discomfort in the arms, jaw, back, or neck, pain, tension, and weakness upon walking that subsides during periods of rest, shakiness in the legs, arms, hands, or feet, swelling of the face, fingers, feet, or lower legs, trembling or shaking of the hands or feet, vomiting of blood or material that looks like coffee grounds, Bluish-colored lips, fingernails, or palms. Change positions slowly until your body is used to the medication. Other side effects not listed may also occur in some patients. FOIA Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Please note that only the generic name of each medication is listed below. The https:// ensures that you are connecting to the